User:Kawaji/120209 resource browser memo
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To-do
- [general] reasonable scheme to refresh properties
- [general] add search box to search "genes, samples, or motifs" from their names (=> Al's point 3 at 2nd March); in progress
- [general] make search "case-insensitive".
- [general] keyword search box should find synonyms too.
- [Expression graph] add "short description" in the graph visible (ex. EntrezGene: 2597)
- [TF expression enrichment] CAGE peak ID => short description
- [Sample page] add link to its parent ontology
- [TF list] add "transcription factor" property to gene based on https://fantom5-collaboration.gsc.riken.jp/wiki/index.php/File:FANTOM5_Transcriptional_regulator_list_March2012AL.xls . So that we can make a query to list all transcription factors
- Browse_gene page should have a search box for genes only. (and other pages too)
- [GOstat] Motif => GO enrichment (from Erik)
- [FF enrichment] https://fantom5-collaboration.gsc.riken.jp/webdav/home/kawaji/120322-FFontology/v6_ontology_term_enrichment/
To-do (in future)
- [general] import the other "facet" from FONSE - not yet. FONSE is not updated.
- re order samples in a meaningful manner
- group replicates and generate average with SD
- consider Anthony's request - see [fantom5:01500]
Wishlist for javascript
- network with cytoscepeWeb / canvasxpress
- dynamic filtering of sample names
- heatmap with canvasexpress
- sortable barchart
Access point
[done]
FF ontologies
[done]
- Load FF ids by using template
[to be done]
- Load other ontologies (such as UBERON) by using template
- Update FF ontology when Chris updated
Swissregulon motifs
[done]
- Load swissregulon motif
- top motifs
- assign properties to each sample page, based on https://fantom5-collaboration.gsc.riken.jp/webdav/home/mdehoon/MotifActivity/mm9/mm9.toptfs.txt.bz2
- top_motifs are (i) comma, and (ii) semicolon separated, such as${MOTIF_NAME};${Z_VALUE},${MOTIF_NAME}:${Z_VALUE},...
{TopMotifsInMaraPhase1
|top_motifs=ALX1.p1;2.17630682572,ALX4.p1;1.87630682572,
}
- motif activities
- assign activities to each Swissregulon motif
- activities are comma separated
{MotifActivitiesInMaraPhase1
|motif_activities= 0.139020440771,-0.287767627519
}
- add sequence logo for swissregulon motif
EntrezGene
[done]
- https://fantom5-collaboration.gsc.riken.jp/files/data/shared/external/entrez_gene/2012-01-19/DATA/GENE_INFO/Mammalia/Homo_sapiens.gene_info.gz
- https://fantom5-collaboration.gsc.riken.jp/files/data/shared/external/entrez_gene/2012-01-19/DATA/GENE_INFO/Mammalia/Mus_musculus.gene_info.gz
- https://fantom5-collaboration.gsc.riken.jp/files/data/shared/external/entrez_gene/2012-01-19/00README.txt
page name
- EntrezGene:${NUMBER}
Individual column's property (from README file)
- tax_id:
- GeneID:
- Symbol:
- LocusTag:
- Synonyms:
- dbXrefs:
- chromosome:
- map location:
- description:
- type of gene:
- Symbol from nomenclature authority:
- Full name from nomenclature authority:
- Nomenclature status:
- Other designations:
- Modification date:
Transcription factors
[to be done]
CAGE peaks
[done]
data
- [human] https://fantom5-collaboration.gsc.riken.jp/webdav/home/kawaji/111220-DPI/hg19/description120126/tc.decompose_smoothing_merged.ctssMaxCounts11_ctssMaxTpm1.tpm.selected.clustername_update.desc.osc.txt.gz
- [mouse] https://fantom5-collaboration.gsc.riken.jp/webdav/home/kawaji/111220-DPI/mm9/description120126/tc.decompose_smoothing_merged.ctssMaxCounts11_ctssMaxTpm1.tpm.selected.clustername_update.desc.osc.txt.gz
page name
- FFCP_PHASE1_hg19::chr1:123..456,+
- FFCP_PHASE1_mm9::chr1:123..456,+
feature
- id (ex. FFCP_PHASE1_hg19::chr1:123..456,+ )
- short_description
- description
- association_with_transcript
- EntrezGene
- HGNC (only for human)
- UniProt
- phase1_expression (comma separated, in the same order to column)
ab-initio motifs
- Sebastian, Ulf and Vlad (KAUST) - http://cbrc.kaust.edu.sa/~uschaefer/ft5motifs/
- Michael , Chistian - HOMER - http://homepages-nw.uni-regensburg.de/~www10894/results.html
- Seva , Ivan (VIGG team) - ChIPMunk - http://line.imb.ac.ru/FANTOM/r2_denovo/report.html
Individual pages
Motif Activity Page
[to be done]
- link to the swissregulon motifs
- link to heat map